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calendary November 19, 2025

An innovative gel for the treatment of tooth decay

Researchers at the University of Nottingham (UK), together with other researchers from the international community, presented to the general public their development for restoring tooth enamel, the news of which immediately spread around the globe. The fact is that if the gel developed by scientists really turns out to be so effective, then this development can be considered a revolution in the field of dentistry. 

The destruction of enamel is the main cause of tooth decay and is associated with dental problems that affect almost 50 % of the world's population. According to WHO, about 3.7 billion people suffer from diseases of the oral cavity associated with the destruction of enamel. 

Unfortunately, the enamel does not recover naturally. Currently, there is no solution that could effectively restore it. Modern treatments such as fluoride lacquers and remineralization solutions only alleviate the symptoms.

The dental gel for the regeneration of the protective layer of teeth of the University of Nottingham team was developed on the basis of protein compounds, which, after application to the damaged tooth surface, form a thin coating that penetrates into microcracks and cavities of the enamel. Such a framework attracts calcium ions and phosphate ions from saliva, triggering the mineralization process. As a result, nanocrystals are formed that fuse with existing tissue. 

Two weeks after application, the enamel structure is restored to a healthy tooth, which is confirmed by research published in the journal Nature.

The new material can also be applied to exposed dentin (exposed areas under the enamel), creating an enamel-like layer that has many benefits, including treating hypersensitivity.

The Mintech-Bio startup plans to bring this product to the market as early as 2026.

 

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